Author(s): Purser S, Moore PR, Swallow S, Gouverneur V
Abstract Share this page
Abstract It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.
This article was published in Chem Soc Rev
and referenced in Biochemistry & Analytical Biochemistry