alexa Followup of adolescents initially treated for prepubertal-onset major depressive disorder with imipramine.


Journal of Psychology & Psychotherapy

Author(s): Hughes CW, Preskorn SH, Wrona M, Hassanein R, Tucker S

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Abstract This preliminary followup of adolescents (n = 16) with prepubertal-onset major depressive disorder (MDD) suggests that a significant number continue to be depressed or possibly depressed (62\%) and have moderate to severe ongoing psychosocial adjustment problems. A concomitant diagnosis of conduct or oppositional disorder at index assessment was a risk factor for an increased incidence of interim depressive episodes and more severe psychosocial adjustment problems including alcohol and drug abuse.
This article was published in Psychopharmacol Bull and referenced in Journal of Psychology & Psychotherapy

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