alexa Friedreich ataxia-update on pathogenesis and possible therapies.


International Journal of Neurorehabilitation

Author(s): Voncken M, Ioannou P, Delatycki MB

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Abstract Friedreich ataxia is the most-common inherited ataxia. Since the causative genetic basis was described in 1996, much has been learnt about the pathogenesis from human, animal, and yeast studies. This has led to the development of rational therapeutic approaches. In this review, the current state of knowledge regarding the pathogenesis of Friedreich ataxia is presented and possible therapeutic strategies based on this knowledge are discussed. This article was published in Neurogenetics and referenced in International Journal of Neurorehabilitation

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