Author(s): Abbas AK, Murphy KM, Sher A
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Abstract The existence of subsets of CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses. Defining the cellular and molecular mechanisms of helper-T-cell differentiation should lead to rational strategies for manipulating immune responses for prophylaxis and therapy.
This article was published in Nature
and referenced in Journal of Clinical & Cellular Immunology