alexa Gastrointestinal stromal tumors (GIST) and laparoscopic resection.


Journal of Gastrointestinal & Digestive System

Author(s): Basu S, Balaji S, Bennett DH, Davies N

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Abstract AIM: To review management, outcome and the lessons learnt from a laparoscopic approach to GISTs. METHOD: All cases of GIST presenting to the upper GI MDT between 2000 and 2006 were reviewed. Presentation, preoperative investigations, management and follow-up were recorded. Surgical resection using a laparoscopic approach, where feasible was the preferred management. RESULTS: 25 consecutive patients that included one oesophageal, three oesophago-gastric, 19 gastric and two smallbowel GISTs were treated between 2000 and 2006. There were 11 male and 14 females with a median age of 68 (25-90) years. Clinical presentation was: gastrointestinal bleed 15, pain 6, dysphagia 2, anaemia 3, weight loss 1, and asymptomatic 2. Out of 25, four were inoperable and treated with imatinib. 17 laparoscopic (including 2 conversions) and four open procedures were performed. Two (both GISTs close to the oesophago-gastric junction) required reoperation due to surgical-related morbidity. Of the 25, five were high-, 11 intermediate- and nine low-risk GISTs. No recurrences in follow-up (median 24, range 6-75) months was observed. CONCLUSION: GISTs can safely and effectively be treated laparoscopically although larger GISTs in difficult anatomical locations may require open surgery. This article was published in Surg Endosc and referenced in Journal of Gastrointestinal & Digestive System

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