alexa Gd3+ cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation.


Journal of Clinical & Cellular Immunology

Author(s): Stasiuk GJ, Smith H, WylezinskaArridge M, Tremoleda JL, Trigg W,

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Abstract Formyl Peptide Receptors (FPRs) are vital in the host inflammatory response, playing an important regulatory role in multiple diseases. A Gd(III) DOTA conjugate of cFLFLFK has been synthesised which targets and visualises FPR1 upon leukocytes in the inflammatory response via magnetic resonance imaging for the first time. This article was published in Chem Commun (Camb) and referenced in Journal of Clinical & Cellular Immunology

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