alexa Gene doping: the hype and the harm.
Clinical Research

Clinical Research

Journal of Clinical Research & Bioethics

Author(s): McKanna TA, Toriello HV

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"Gene doping" is the term used to describe the potential abuse of gene therapy as a performance-enhancing agent. Gene doping would apply the techniques used in gene therapy to provide altered expression of genes that would promote physical superiority. For example, insulin-like growth factor 1 (IGF-1) is a primary target for growth hormone; overexpression of IGF-1 can lead to increased muscle mass and power. Although gene doping is still largely theoretical, its implications for sports, health, ethics, and medical genetics are significant.

This article was published in Pediatr Clin North Am and referenced in Journal of Clinical Research & Bioethics

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