Journal of Trauma & Treatment

Author(s): Szendri

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Giant cell tumour (GCT) is still one of the most obscure and intensively examined tumours of bone. Its histogenesis is uncertain. The histology does not predict the clinical out- come; and there are still many unanswered questions with regard to both its treatment and prognosis. The World Health Organisation has classified GCT as “an aggressive, potentially malignant lesion”, 1 which means that its evolution based on its histological features is unpre- dictable. Statistically, 80% of GCTs have a benign course, with a local rate of recurrence of 20% to 50%. About 10% undergo malignant transformation at recurrence and 1% to 4% give pulmonary metastases even in cases of benign his- tology

This article was published in THE JOURNAL OF BONE AND JOINT SURGERY and referenced in Journal of Trauma & Treatment

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