Author(s): StephensonBrown A, Wang HC, Iqbal P, Preece JA, Long Y,
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Abstract Saccharides - a versatile class of biologically important molecules - are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect d-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely d-galactose, d-fructose and d-mannose.
This article was published in Analyst
and referenced in Journal of Biosensors & Bioelectronics