Author(s): Novelli F, Recine M, Sparatore F, Juliano C
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Abstract Seven gold complexes were prepared and investigated for biocidal activity against Gram-positive and -negative bacteria, fungi and protozoa. All of them were active against the tested microorganisms with the exception of Pseudomonas aeruginosa. In many, cases minimum inhibitory concentrations (MIC) were well below 1 microgram/ml. The activity is not simply related to the gold content, but also to the nature of both the phosphine and the aminothiol to which the metal is bound.
This article was published in Farmaco
and referenced in Biochemistry & Pharmacology: Open Access