alexa Granulomas in sympathetic ophthalmia and sarcoidosis. Immunohistochemical study.
Cardiology

Cardiology

Journal of Vasculitis

Author(s): Chan CC, BenEzra D, Hsu SM, Palestine AG, Nussenblatt RB

Abstract Share this page

Abstract Monoclonal antibodies were used to identify cells that form choroidal granulomas and Dalen-Fuchs nodules in sympathetic ophthalmia as well as the granulomas of sarcoid. Immunohistochemical analysis of frozen sections of fresh human tissues obtained after enucleation (sympathetic ophthalmia) and lung biopsy (sarcoid) was performed by the avidin-biotin-peroxidase complex method. The majority of the inflammatory cells within these lesions were identical and were composed mainly of cells originating from bone marrow-derived monocytes (reticuloendothelial system) probably representing immunologically stimulated granulomas. This study suggests possible immune phenomena that may take part in the pathogenesis of sympathetic ophthalmia and provides some insights into the possible mechanism of formation of choroidal granulomas and Dalen-Fuchs nodules in this disease.
This article was published in Arch Ophthalmol and referenced in Journal of Vasculitis

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords