alexa Guidelines for the programmatic management of drug-resistant tuberculosis: emergency update 2008


Clinical Microbiology: Open Access

Author(s): World Health Organization

Abstract Share this page

Multidrug-resistant tuberculosis (MDR-TB), defined as TB caused by organisms that are resistant to isoniazid and rifampicin, two first-line antiTB drugs, continues to threaten the progress made in controlling the disease. The emergence of extensively drug-resistant TB (XDR-TB), defined as MDR-TB that is resistant as well to any one of the fluoroquinolones and to at least one of three injectable second-line drugs (amikacin, capreomycin or kanamycin), has heightened this threat. XDR-TB has been identified in all regions of the world since 2006. Treatment outcomes are significantly worse in XDR-TB patients than in MDR-TB patients. Outbreaks of XDRTB in populations with high prevalence of HIV have caused alarmingly high mortality rates. The emergence of XDR-TB as a new threat to global public health demands that health officials and health-care providers respond with a coordinated strategy drawing on the Stop TB Strategy.1 Guidelines for the programmatic management of drug-resistant tuberculosis: emergency update 2008 provides updated guidelines and recommendations on how to manage drug-resistant TB (DR-TB) based on a rapid assessment of the best available evidence by a group of experts. A fully revised second edition will be published in 2010, following WHO guidance on retrieval, synthesis and grading of evidence. Until that time, the emergency update serves as interim guidance for TB control programmes and medical practitioners on all aspects of the management of DR-TB, including XDR-TB. It contains 19 chapters based on the original 18 chapters from the first edition published by the World Health Organization in 20062 plus an additional chapter on patient-centered care.

  • To read the full article Visit
  • Open Access
This article was published in WHO and referenced in Clinical Microbiology: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version