Author(s): Krammer F, Margine I, Hai R, Flood A, Hirsh A,
Abstract Share this page
Abstract The recent outbreak of H7N9 influenza virus infections in humans in China has raised concerns about the pandemic potential of this strain. Here, we test the efficacy of H3 stalk-based chimeric hemagglutinin universal influenza virus vaccine constructs to protect against H7N9 challenge in mice. Chimeric hemagglutinin constructs protected from viral challenge in the context of different administration routes as well as with a generic oil-in-water adjuvant similar to formulations licensed for use in humans.
This article was published in J Virol
and referenced in Journal of Vaccines & Vaccination