Author(s): Brackertz D, Isler E, Kueppers F
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Abstract The half-life of 125I labelled C1INH was determined in patients with HAE and normal controls. There was no significant difference between these two groups. The half-life in the HAE patients was 67.7 hr +/- 4.9 hr (s.d.) and in the normals 64 hr +/- 1.4 hr (s.d.). This finding is consistent with a defect in synthesis as an explanation of the low serum C1INH levels in HAE patients.
This article was published in Clin Allergy
and referenced in Journal of Hematology & Thromboembolic Diseases