Author(s): Rawe VY, Boudri HU, Alvarez Sed C, Carro M, Papier S,
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Abstract Magnetic activated cell sorting (MACS) with annexin V microbeads recognizes externalized phosphatidylserine (PS) residues on the surface of apoptotic spermatozoa. The successful use of this novel technique applied to a highly apoptotic semen sample before performing intracytoplasmic sperm injection (ICSI) is reported here. The use of annexin V microbeads for selecting non-apoptotic spermatozoa seems to reduce the percentage of altered cells, improving the chance of pregnancy after ICSI. Copyright 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
This article was published in Reprod Biomed Online
and referenced in Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology