alexa Hereditary breast and ovarian cancer and other hereditary syndromes: using technology to identify carriers.
Oncology

Oncology

Journal of Carcinogenesis & Mutagenesis

Author(s): Drohan B, Roche CA, Cusack JC Jr, Hughes KS

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Abstract PURPOSE AND METHODS: Most patients who harbor a genetic mutation for hereditary breast cancer have not been identified, despite the availability of genetic testing. Developing an effective approach to the identification of high-risk individuals is the key to preventing and/or providing early diagnosis of cancer in this patient population. This educational review addresses these issues. RESULTS AND DISCUSSION: Using data available on the internet, and making assumptions regarding the types and results of genetic testing, we have estimated the number of mutation carriers in the country and the number who have been tested and identified as such. Overall, our ability to fund and more effectively manage carriers is weak. A technological solution is discussed. This article was published in Ann Surg Oncol and referenced in Journal of Carcinogenesis & Mutagenesis

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