Author(s): Daheshia M, Feldman LT, Rouse BT
Abstract Share this page
Abstract Following infection, herpes simplex virus establishes latency in the nervous system and recurrences of lytic replication occur periodically. Molecular events which may determine how virus enters latency, how it is maintained and what occurs during reactivation have been investigated. The role of the immune response in limiting infection of the nervous system, influencing the latent state and removing virus from peripheral sites following reactivation has also been studied.
This article was published in Curr Opin Microbiol
and referenced in Journal of Vaccines & Vaccination