alexa Hiding in plain sight: a closer look at posterior cortical atrophy.


Journal of Neuropsychopharmacology & Mental Health

Author(s): Beh SC, Muthusamy B, Calabresi P, Hart J, Zee D,

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Abstract Posterior cortical atrophy (PCA) is a neurodegenerative syndrome dominated by deterioration of higher visual function (particularly visuospatial and visuoperceptual abilities). It is most commonly due to Alzheimer's disease pathology, but may also be caused by dementia with Lewy bodies, corticobasal degeneration or Creutzfeldt-Jakob disease. Patients often present to optometrists, ophthalmologists and/or neurologists with non-specific visual complaints, and unless clinicians seek the specific symptoms and signs of PCA (beyond that of the 'standard' neurological examination), this infrequent disorder is easily missed, delaying its diagnosis and treatment. We review the clinical features of PCA, focusing on its visual manifestations, to help neurologists recognise this important syndrome. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to This article was published in Pract Neurol and referenced in Journal of Neuropsychopharmacology & Mental Health

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