alexa High blood pressure as risk factor and prognostic predictor in acute ischaemic stroke: when and how to treat it?
Cardiology

Cardiology

Journal of Hypertension: Open Access

Author(s): Bath P

Abstract Share this page

Abstract High blood pressure is common in the western world and is a major risk factor for the development of stroke. Lowering blood pressure reduces the risk of first and recurrent stroke. High blood pressure is also common in acute stroke and is independently associated with a poor prognosis, in part due to promoting early recurrence and the development of fatal cerebral oedema in patients with ischaemic stroke and, possibly, re-bleeding in those with haemorrhagic stroke. However, the management of blood pressure remains an enigma--its lowering could improve outcome by reducing recurrence or worsen outcome by reducing regional perfusion in the face of dysfunctional cerebral autoregulation. Conversely, raising blood pressure might improve outcome by raising regional perfusion or worsen it by inducing cerebral oedema and early recurrence. Administration of some vaso-active drugs (beta-receptor antagonists and calcium channel blockers) can worsen outcome and reduce cerebral blood flow. In contrast, other drug classes--angiotensin- converting enzyme inhibitors, angiotensin receptor antagonists and nitrates--appear to lower blood pressure without reducing measures of cerebral perfusion. In the absence of definitive trial data, which is urgently needed, blood pressure should not be routinely lowered unless it is extreme (systolic blood pressure >220 mm Hg) or associated with arterial dissection or cardiac ischaemia or failure, in which case cautious lowering (<15\%), perhaps with an angiotensin-converting enzyme inhibitor, angiotensin receptor antagonist or nitrate, is appropriate. Copyright 2004 S. Karger AG, Basel This article was published in Cerebrovasc Dis and referenced in Journal of Hypertension: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords