alexa High prevalence of Hepatitis E virus in French domestic pigs.
Microbiology

Microbiology

Journal of Antivirals & Antiretrovirals

Author(s): Rose N, Lunazzi A, Dorenlor V, Merbah T, Eono F

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Abstract The importance of the domestic pig reservoir for Hepatitis E virus (HEV) was assessed by estimating the seroprevalence and prevalence of HEV contaminated livers in French slaughter-aged pigs. 6565 sera and 3715 livers were randomly sampled from 186 pig farms throughout the country. Taking the sampling design into account, the farm-level seroprevalence was 65\% (95\% CI 57-74) and 31\% (95\% CI 24-38) of the slaughter-aged pigs had antibodies against HEV. The individual prevalence of HEV RNA positive livers was 4\% (95\% CI 2-6) and 24\% (95\% CI 17-31) of the farms had at least 1 positive liver. Most isolates were of genotype 3f (76.7\%) with smaller amounts of 3c (18.6\%) and 3e (4.6\%). The high prevalence of HEV in pigs and the similarities between HEV subtypes from pigs and humans corroborates the possible zoonotic origin of some HEV autochthonous infections. Copyright © 2011 Elsevier Ltd. All rights reserved.

This article was published in Comp Immunol Microbiol Infect Dis and referenced in Journal of Antivirals & Antiretrovirals

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