alexa High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nationwide survey.
Medicine

Medicine

Internal Medicine: Open Access

Author(s): AguilarSalinas CA, Olaiz G, Valles V, Torres JM, Gmez Prez FJ,

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Abstract The prevalence of lipid abnormalities revealed in a survey done in 417 Mexican cities is described. Information was obtained on 15,607 subjects, aged 20 to 69 years. In this report, only samples obtained after a 9- to 12-h fast were included (2,256 cases: 953 men and 1,303 women). The population is representative of Mexican urban adults. Mean lipid concentrations were: cholesterol, 4.80 mmol/l; triglycerides, 2.39 mmol/l; HDL cholesterol, 1.00 mmol/l; and LDL cholesterol, 3.06 mmol/l. The most prevalent abnormality was HDL cholesterol below 0.9 mmol/l (46.2\% for men and 28.7\% for women). Hypertriglyceridemia (>2.26 mmol/l) was the second most prevalent abnormality (24.3\%). Severe hypertriglyceridemia (>11.2 mmol/l) was observed in 0.42\% of the population. Increased LDL cholesterol (> or =4.21 mmol/l) was observed in 11.2\% of the sample. Half of the hypertriglyceridemic subjects had a mixed dyslipidemia or low HDL cholesterol. More than 50\% of the low HDL cholesterol cases were not related to hypertriglyceridemia. Insulin resistance was found in 59\% of them. In conclusion, the prevalence of hypoalphalipoproteinemia and other forms of dyslipidemia in Mexican adults is very high and it is among the highest previously reported worldwide.
This article was published in J Lipid Res and referenced in Internal Medicine: Open Access

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