Author(s): Woodcock CL, Dimitrov S
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Abstract The linear array of nucleosomes that comprises the primary structure of chromatin is folded and condensed to varying degrees in nuclei and chromosomes forming 'higher order structures'. We discuss the recent findings from novel experimental approaches that have yielded significant new information on the different hierarchical levels of chromatin folding and their functional significance.
This article was published in Curr Opin Genet Dev
and referenced in Journal of Gerontology & Geriatric Research