Author(s): Potthoff A, Brockmeyer NH, Potthoff A, Brockmeyer NH
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Abstract While classical Kaposi sarcoma is a slowly progressing tumor, AIDS-related Kaposi sarcoma is much more aggressive. After introduction of antiretroviral therapy and with the use of well- tolerated chemotherapeutic agents, complete remission of the tumor can be achieved. Local therapeutic options include excision, cryosurgery, radiation and alitretinoin gel. In 45 \% of patients with more than 400/microl CD4+ lymphocytes, interferon-alpha induces complete remission. New concepts of pathogenesis lead to therapeutic targets, such as inhibition of angiogenesis.
This article was published in J Dtsch Dermatol Ges
and referenced in Journal of AIDS & Clinical Research