alexa Hormonal therapy in the management of prostate cancer: from Huggins to the present.
Molecular Biology

Molecular Biology

Journal of Cytology & Histology

Author(s): Garnick MB

Abstract Share this page

Abstract Hormonal therapy has been the mainstay of treatment for advanced forms of prostate cancer. Although early clinical studies suggested that major improvements and even cure could occur, later randomized prospective investigations showed that hormonal treatments were palliative rather than curative. Subsequent studies have suggested, but not conclusively proven, that earlier initiation of hormonal therapy for patients with early forms of metastatic disease may prolong disease-free and overall survival. The choice of hormonal agents, either alone as monotherapy or in combination with agents of differing mechanisms of action, suggests that further improvements in survival can be achieved with combinations of hormonal agents. Many studies have suggested that the use of hormonal therapy with localized forms of prostate cancer may provide pathologic benefit in decreasing the amount of tumor found at the time of radical prostatectomy or treated during radiation therapy. Although short-term outcomes looking at tumor "downstaging" have been positive, longer follow-up will be necessary before definitive conclusions can be made regarding the ultimate utility of preoperative or preradiation therapy hormonal treatments (neoadjuvant hormonal therapy).
This article was published in Urology and referenced in Journal of Cytology & Histology

Relevant Expert PPTs

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]online.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords