Author(s): del Mar Tomas M, Cartelle M, Pertega S, Beceiro A, Llinares P,
Abstract Share this page
Abstract Between October 2001 and August 2002, 30 hospital patients became infected or colonised by a multiresistant (including to carbapenems) epidemic strain of Acinetobacter baumannii (AbMR) in a hospital outbreak. This study analysed the risk-factors associated with acquisition of this epidemic strain and investigated the prognosis of patients infected by AbMR, with the aim of elucidating factors which lead to mortality. A case-control study of the acquisition of AbMR in patients infected or colonised in the hospital outbreak was performed. Independent risk-factors leading to death were studied by logistic regression analysis. Multivariate analysis of the risk-factors for colonisation/infection with AbMR revealed an independent association with the presence of an arterial catheter (OR, 1.13; 95\% CI, 1.03-1.25) and administration of imipenem as monotherapy (OR, 11.12; 95\% CI, 2.33-53.09). Multivariate analysis of the prognostic features leading to mortality revealed a significant association with hypotension or shock (OR, 24.63; 95\% CI, 1.56-387.56) at the time of bacterial isolation.
This article was published in Clin Microbiol Infect
and referenced in Biochemistry & Pharmacology: Open Access