alexa Human fecal PCDD F-excretion exceeds the dietary intake.
Environmental Sciences

Environmental Sciences

Journal of Bioremediation & Biodegradation

Author(s): Schrey P, Wittsiepe J, Mackrodt P, Selenka F

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Abstract A mass balance of human dietary PCDD/F-intake and fecal PCDD/F-excretion was carried out. The participants of the study were seven male and seven female adults between the ages of 24 to 64 years, living in North Rhine-Westphalia, Germany. The PCDD/F-intake was measured using the duplicate method. Sampling time of each food duplicate covered three days. The fecal PCDD/F-excretion was measured by collecting the feces which corresponded to the food duplicates. The mean daily dietary PCDD/F-intake was 49 pg I-TEq/d (range: 23-96 pg I-TEq/d) and therewith lower than that estimated in the past. The mean daily fecal PCDD/F-excretion was 98 pg I-TEq/d (40-200 pg I-TEq/d). This is twice the amount of the PCDD/F-intake. The fecal excretion of OCDD was especially higher than the dietary intake (mean: 7 fold, range: 1.2-21 fold). The differences between PCDD/F-intake and PCDD/F-excretion may be caused by a reduction of the body burden as a consequence of decreasing PCDD/F-intake. Other explanations were additional sources of exposure to PCDD/F or de novo formation of PCDD/F in the human body.
This article was published in Chemosphere and referenced in Journal of Bioremediation & Biodegradation

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