alexa Human immunodeficiency virus infection and invasive cervical cancer in South Africa.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Lomalisa P, Smith T, Guidozzi F, Lomalisa P, Smith T, Guidozzi F

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Abstract PURPOSE: The goal of this study was to determine whether South African HIV-seropositive women with invasive cervical cancer present with disease that is more advanced than that of HIV-seronegative women and whether degree of immunosuppression affects the extent of disease at initial presentation. METHODS: This study is a retrospective review of 60 HIV-seropositive and 776 HIV-seronegative new cases of invasive cervical carcinoma seen at the combined gynecologic oncology unit of the University of the Witwatersrand, Johannesburg, South Africa. RESULTS: The HIV seroprevalence was 7.2\%. Squamous cell carcinoma was the histologic subtype in more than 90\% of both cohorts of patients. Although the HIV-positive patients presented with invasive cervical cancer almost 10 years earlier than the HIV-negative patients, i.e., mean age 44 years +/- 9.8 versus 53 years +/- 12.7, respectively (P
  • DOI: 10.1006/gyno.2000.5775
  • This article was published in Gynecol Oncol and referenced in Journal of AIDS & Clinical Research

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