alexa Human rabies in China.
Immunology

Immunology

Journal of Vaccines & Vaccination

Author(s): YongZhen Zhang, ChengLong Xiong, DongLou Xiao, RenJie Jiang, ZhaoXiao Wang

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During the 55-year period, 108,412 human rabies cases were recorded in China. The Figure shows the number of annual cases from 1950 to 2004; 3 major epidemics of human rabies in China are apparent. In the early 1950s, only a few cases occurred; the first peak occurred from 1956 to 1957 with ≈,000 cases each year. Then the number of cases declined during subsequent years and was relatively constant throughout the 1960s. By 1969, the number of cases increased again to ≈,000. This ascending phase continued throughout the 1970s and 1980s. The second epidemic peaked in the early 1980s. In 1981, 7,037 cases were recorded, the largest number of cases in a single year during the 55-year period. During the 1980s, 55,367 cases were reported (>5,000 cases annually), representing >50% of the 108,412 cases seen during the entire period. In the early 1990s, the number of human cases decreased dramatically from 3,520 in 1990 to 159 in 1996. However, this downward trend reversed its course in 1998, and annual cases have increased gradually since then. In 2004, a total of 2,651 cases were reported, an increase of >16 fold when compared with the numbers in 1996. This third rabies epidemic apparently has not yet peaked.

This article was published in Emerg Infect Dis and referenced in Journal of Vaccines & Vaccination

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