alexa Human Th17 cells: are they different from murine Th17 cells?


Journal of Clinical & Cellular Immunology

Author(s): Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S

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Abstract Type 17 Th (Th17) cells have been identified as a distinct population of CD4(+) effector T cells different from Th1 and Th2 cells. While the pre-eminent cytokine of Th1 cells is IFN-gamma and that of Th2 cells is IL-4, the distinctive cytokine of Th17 cells is IL-17A. However, although murine and human Th1 and Th2 cells exhibit strong similarities, human and murine Th17 cells seem to differ in several aspects. This article was published in Eur J Immunol and referenced in Journal of Clinical & Cellular Immunology

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