Author(s): Kwon MS, Lim SW, Kwon HM
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Abstract The interstitium of the renal medulla is hypertonic, imposing deleterious effects on local cells. At the same time, the hypertonicity provides osmotic gradient for water reabsorption and is a local signal for tissue-specific gene expression and differentiation of the renal medulla, which is a critical organ for water homeostasis.
This article was published in Physiology (Bethesda)
and referenced in Biochemistry & Pharmacology: Open Access