Author(s): Sharma A, Mathur R, Dixit VP
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Abstract Administration of S. anacardium nut shell extract to cholesterol fed rabbits resulted in a significant reduction in serum cholesterol (-73.3\%) and serum LDL-Chol. (-80\%). The extract feeding also prevented the accumulation of cholesterol/triglycerides in liver, heart muscle and aorta and caused a regression of plaques (75.3-83.5\%). These results indicate that S. anacardium is hypocholesterolemic in action and prevents cholesterol induced atheroma. Possible mechanism of action is discussed.
This article was published in Indian J Exp Biol
and referenced in Medicinal Chemistry