Author(s): Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E
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Abstract Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.
This article was published in Lancet
and referenced in Journal of Addiction Research & Therapy