alexa Hypocretin (orexin) deficiency in human narcolepsy.
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E

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Abstract Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission. This article was published in Lancet and referenced in Journal of Addiction Research & Therapy

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