Author(s): Thirumalai T, Therasa SV, Elumalai EK, David E
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Abstract OBJECTIVE: To evaluate the hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rats. METHODS: Hypoglycemic activity of Brassica juncea (seeds) aqueous extract at a dose of 250, 350 and 450 mg/kg body weight was evaluated. Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated. RESULTS: The serum insulin levels were recorded a significant depletion in all groups, short term as well as long term diabetic animals, when compared to that of normal animals. A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups. CONCLUSIONS: The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat.
This article was published in Asian Pac J Trop Biomed
and referenced in Journal of Diabetes & Metabolism