alexa Hypovitaminosis D as a risk factor of hip fracture severity.


Journal of Gerontology & Geriatric Research

Author(s): Larrosa M, Gomez A, Casado E, Moreno M, Vzquez I,

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Abstract SUMMARY: In a cross-sectional study including 324 patients older than 65 years admitted to our hospital for osteoporotic hip fracture, we found that those patients with a more severe vitamin D deficiency had more severe osteoporotic hip fractures (Garden grades III-IV and Kyle III-IV). INTRODUCTION: To identify possible differences in baseline characteristics of patients with different types of osteoporotic hip fracture. METHODS: Cross-sectional study including consecutive individuals over 65 admitted to our hospital for osteoporotic hip fracture over a year. Demographic data, fracture type, comorbidities, history of osteoporosis, functional capacity, nutritional status and vitamin D storage were evaluated. RESULTS: We included 324 patients (83 ± 7 years, 80\% women). Two hundred sixteen patients (67\%) had vitamin D deficiency (25OHD3 <25 ng/ml). In patients with severe femoral neck or intertrochanteric fractures (Garden III-IV and Kyle III-IV), vitamin D deficiency was more frequent (74\%) and severe (25OHD3 20 ± 15 ng/ml) than in patients with less severe fractures (57\%, 25OHD3 26 ± 21 ng/ml). Forty-three percent of patients had previous fractures. Only 15\% of patients had been previously diagnosed with osteoporosis and 10\% were receiving treatment. Patients receiving vitamin D supplements have higher 20OHD3 levels and less severe fractures. CONCLUSIONS: Although vitamin D levels are not different between patients with intracapsular or extracapsular hip fractures, a more severe vitamin D deficiency seems to be associated to more severe osteoporotic hip fractures. A prior vitamin D supplementation could avoid a higher severity of these fractures. This article was published in Osteoporos Int and referenced in Journal of Gerontology & Geriatric Research

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