alexa Hypoxia inducible factor-1 expression mediates myocardial response to ischemia late after acute myocardial infarction
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Parisi Q, BiondiZoccai GG, Abbate A, Santini D, Vasaturo F

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We report hypoxia-inducible factor-1 (HIF-1) expression in myocardium of patients with recent acute myocardial infarction (AMI), supporting the hypothesis of HIF-1 as a possible mediator of response to ischemia. A potential diagnostic role of determining tissue expression of HIF-1 as a marker of ischemia, and potential therapeutic implications by trying to modulate HIF-1 activity in order to promote beneficial effects of HIF-1 related genes (e.g. expression of vascular endothelial growth factor (VEGF)) may derive

This article was published in Int J Cardiol. and referenced in Journal of Diabetes & Metabolism

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