alexa Hypoxic-ischemic brain injury in the term infant-current concepts.


Journal of Clinical & Cellular Immunology

Author(s): Shalak L, Perlman JM

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Abstract An enhanced understanding of the cellular characteristics contributing to ongoing brain injury following intrapartum hypoxia-ischemia has resulted in the implementation of targeted neuroprotective strategies in the newborn period. This review briefly covers the pathogenesis of hypoxic-ischemic injury with an emphasis on reperfusion injury; the role of magnetic resonance imaging in the detection of such injury, and focuses on potential strategies both supportive and neuroprotective to prevent ongoing injury with a specific emphasis on modest hypothermia. This article was published in Early Hum Dev and referenced in Journal of Clinical & Cellular Immunology

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