alexa Identifying gene and protein mentions in text using conditional random fields.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Computer Science & Systems Biology

Author(s): McDonald R, Pereira F

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Abstract BACKGROUND: We present a model for tagging gene and protein mentions from text using the probabilistic sequence tagging framework of conditional random fields (CRFs). Conditional random fields model the probability P(t/o) of a tag sequence given an observation sequence directly, and have previously been employed successfully for other tagging tasks. The mechanics of CRFs and their relationship to maximum entropy are discussed in detail. RESULTS: We employ a diverse feature set containing standard orthographic features combined with expert features in the form of gene and biological term lexicons to achieve a precision of 86.4\% and recall of 78.7\%. An analysis of the contribution of the various features of the model is provided.
This article was published in BMC Bioinformatics and referenced in Journal of Computer Science & Systems Biology

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