Author(s): Gordon RR, Noble DA, Ward AM, Allen R
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Abstract 250 infants from atopic families were investigated to determine the relation between serum IgE concentrations and the development of atopic symptoms. In 44 (17.6\%) atopy developed before the age of two years, 60 (24\%) had doubtful symptoms, and 146 (58.4\%) were clinically clear. Those who were definitely affected had higher serum IgE than those who were unaffected but 50\% of them had serum IgE within the normal range. 9\% of the clinically unaffected infants had raised serum IgE. Breast-feeding was in no way protective against either the development of atopy or an increase in IgE to abnormal levels.
This article was published in Lancet
and referenced in International Journal of Inflammation, Cancer and Integrative Therapy