Author(s): Miller LH
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Abstract The high mortality from malaria in sub-Sahara Africa selected multiple genes that give the population a selective advantage. Identification of the genetic basis for resistance may suggest unusual approaches to development of malarial vaccines and antimalarial drugs. Some of these genes may be deleterious, although of selective advantage within the African setting, and need to be identified for counseling for disease prevention.
This article was published in Proc Natl Acad Sci U S A
and referenced in Mycobacterial Diseases