alexa Impact of young age on prognosis for head and neck cancer: a matched-pair analysis.


Cosmetology & Oro Facial Surgery

Author(s): Gilroy JS, Morris CG, Amdur RJ, Mendenhall WM

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Abstract BACKGROUND: : The purpose of this study was to review outcomes of young patients (age <40 years) treated with definitive radiotherapy alone for squamous cell carcinoma of the oropharynx, and larynx, and to compare these results with an older matched patient cohort. METHODS: : Since 1983, 30 previously untreated young patients underwent definitive radiotherapy at the University of Florida and were matched with an older group of patients (age >45 years) with respect to primary site, stage of disease, and sex. RESULTS: : There was no difference in cause-specific survival, locoregional control, or long-term complications between the two groups; however, there was a significant difference in overall survival favoring young patients (p = .0174). Older patients had twice as many second malignancies. CONCLUSION: : Young age does not confer a worse prognosis in patients treated with definitive radiotherapy for squamous cell carcinoma of the oropharynx and larynx. This article was published in Head Neck and referenced in Cosmetology & Oro Facial Surgery

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