alexa Importance of the personal endotoxin cloud in school-age children with asthma.


Journal of Clinical & Cellular Immunology

Author(s): Rabinovitch N, Liu AH, Zhang L, Rodes CE, Foarde K,

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Abstract BACKGROUND: A number of studies have observed associations between the amount of endotoxin in urban dust and chronic asthma severity, but a direct relationship between personal exposure to household endotoxin and acute asthma worsening has not yet been defined. OBJECTIVE: We sought to investigate the relationship between day-to-day changes in personal endotoxin exposure and asthma severity. METHODS: In the winter and spring of 1999 through 2000, endotoxin exposures were monitored in asthmatic schoolchildren by using portable, as opposed to stationary, monitors designed to measure inhalable and respirable particulate matter less than or equal to 2.5 and 10 microm in diameter. Children were followed with daily measurements of FEV(1) and asthma symptoms. RESULTS: Over a 24-hour period, median daily personal endotoxin exposures ranged from 0.08 EU/m(3) (measured at a particulate matter size range
  • DOI: 10.1016/j.jaci.2005.08.045
  • This article was published in J Allergy Clin Immunol and referenced in Journal of Clinical & Cellular Immunology

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