alexa Importance of Universal screening for thyroid disorders in first trimester of pregnancy.
Engineering

Engineering

Journal of Textile Science & Engineering

Author(s): Kim YC, Guan KL, Dave A, Maru L, Tripathi M, Dave A, Maru L, Tripathi M

Abstract Share this page

Abstract OBJECTIVE: To determine the importance of screening for Thyriod disorders in the first trimester of pregnancy. MATERIALS AND METHODS: The Study was conducted on 305 patients which were were randomly selected and screened on OPD basis by TSH levels (cut off level 0.10-2.50 mIU/ml). RESULTS: In the 305 women screened mean age was 24.46 years, mean gestational age was 9.09 weeks, 89.83\% were euthyroid, 9.8\%were hypothyroid, 0.32\% were hyperthyroid. Incidence of hypothyroidism in high risk population was 20.58\% and in normal population was 6.7\%. There was significant association of thyroid disorders with high risk factors (P < 0.001). In hypothyroid women 46\% had adverse perinatal outcomes and 53.33\% had normal outcomes. This shows statistically significant association abnormal TSH values with adverse pregnancy outcomes (P < 0.001). In abnormal perinatal outcomes 6.2\% women had Caesarean section out of them 73.68\% were euthyroid, 26.31\% were hypothyroid 1.9\% had preterm labour, out of them 50\% were euthyroid, 50\% were hypothyroid. Out of 2.2\% spontaneous abortions 28.5\% were in euthyroid group while 71.4\% were in hypothyroid group. There was 1 term stillbirth in hypothyroid group. This study showed significant association between abnormal thyroid stimulating hormone (TSH) values and adverse perinatal outcomes (P < 0.001). CONCLUSION: There is significant correlation between risk factors and hypothyroidism. So high risk screening is mandatory in early pregnancy. But if we screen only high risk population we would miss 4.6\% cases which could have been diagnosed and treated earlier. Therefore it is important to screen all pregnant women in the first trimester, it should be made mandatory.
This article was published in Indian J Endocrinol Metab and referenced in Journal of Textile Science & Engineering

Relevant Expert PPTs

Relevant Speaker PPTs

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords