alexa Improved base calling for the Illumina Genome Analyzer using machine learning strategies.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Computer Science & Systems Biology

Author(s): Kircher M, Stenzel U, Kelso J

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Abstract The Illumina Genome Analyzer generates millions of short sequencing reads. We present Ibis (Improved base identification system), an accurate, fast and easy-to-use base caller that significantly reduces the error rate and increases the output of usable reads. Ibis is faster and more robust with respect to chemistry and technology than other publicly available packages. Ibis is freely available under the GPL from http://bioinf.eva.mpg.de/Ibis/.
This article was published in Genome Biol and referenced in Journal of Computer Science & Systems Biology

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