alexa In vitro and in vivo fluoride release from orthodontic elastomeric ligature ties.



Author(s): Wiltshire WA

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Abstract Clinically, demineralization of enamel around orthodontic attachments can occur after only 1 month. Fluoride incorporation into elastomeric ligature ties may provide additional protection against decalcification through fluoride release. This study compared the fluoride release of fluoride-impregnated and nonfluoride elastomeric ligature ties (Ortho Arch Company) both in vitro and in vivo. A total of 260 fluoride-impregnated and 260 nonfluoride elastomerics were evaluated in this study, 400 in vitro and 120 in vivo. For the in vivo part of the study, six patients had fluoride and nonfluoride elastomerics placed in cross-quadrant fashion in their mouths; these were removed and tested for residual fluoride release after 1 month. With the use of the potentiometric analytical method, the fluoride release of the elastomerics was determined in distilled water as the 24-hour residual release, to compare the in vitro and in vivo fluoride leached into solution. The data was analyzed with the Wilcoxon matched-pairs signed ranks test. The distilled water control yielded an F- reading of 0.03 +/- 0.01 microgram/F/mL. In the in vitro part of the study, an average of 0. 38 microgram/F/mL/elastomeric was released over the 1 month period by the fluoride-impregnated elastomerics; this decreased significantly (P <. 05) to a 24-hour residual value at 1 month of 0.02 microgram/F/mL/elastomeric ligature, which is in the same order of magnitude as the distilled water control solution. The nonfluoride ties produced a calculated 24 hour residual fluoride release of 0. 003 microgram/F/mL/elastomeric after 1 month; this is much less than the distilled water control and would not be possible to measure accurately. After 1 month in vivo, significantly greater (P >.05) amounts of 24-hour residual fluoride were apparent: F- elastomerics = 1.43 microgram/F/mL/elastomeric and nonfluoride elastomerics = 0.44 microgram/F/mL/elastomeric. Fluoride ties gained weight intra-orally. Residual, leachable fluoride was present in fluoride-impregnated and nonfluoride elastomeric ligature ties after 1 month of intraoral use, due to imbibition. The clinical efficacy of fluoride-impregnated elastomeric ligature ties to prevent decalcification in the presence of plaque needs to be investigated.
This article was published in Am J Orthod Dentofacial Orthop and referenced in Dentistry

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