alexa In vivo cytogenetic and oxidative stress-inducing effects of cypermethrin in freshwater fish, Channa punctata Bloch.
Agri and Aquaculture

Agri and Aquaculture

Fisheries and Aquaculture Journal

Author(s): Ansari RA, Rahman S, Kaur M, Anjum S, Raisuddin S

Abstract Share this page

Abstract Synthetic pyrethroids are considered to be safe over other insecticides. Many of the newest pyrethroids lack ecotoxicity data. However, animal data indicate that their use may pose risk to environmental biota. The cytogenetic effects of cypermethrin, an α-class type II pyrethroid were evaluated using robust genotoxicity assay of chromosomal aberration (CA) and micronucleus (MN) tests in highly mitotic kidney cells and in erythrocytes of a freshwater fish, Channa punctata Bloch. In order to understand biochemical mechanism of genotoxic effects, oxidative stress parameters were also studied in fish erythrocytes. Fish exposed to cypermethrin (0.4, 0.8 and 1.2 μg/l for 48 and 72 h) showed increased frequencies of CA and MN in a concentration-dependent manner. Fish exposed to positive genotoxin, ethyl methane sulfonate (EMS) also showed significant increase in frequencies of CA and MN. The genotoxic effects were invariably accompanied and correlated with increased oxidative stress and disturbance of antioxidant enzymes. Copyright © 2010 Elsevier Inc. All rights reserved. This article was published in Ecotoxicol Environ Saf and referenced in Fisheries and Aquaculture Journal

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version