alexa In-a-dish: induced pluripotent stem cells as a novel model for human diseases.
Dentistry

Dentistry

JBR Journal of Interdisciplinary Medicine and Dental Science

Author(s): BeltroBraga PC, Pignatari GC, Russo FB, Fernandes IR, Muotri AR

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Abstract Human pluripotent stem cells bring promise in regenerative medicine due to their self-renewing ability and the potential to become any cell type in the body. Moreover, pluripotent stem cells can produce specialized cell types that are affected in certain diseases, generating a new way to study cellular and molecular mechanisms involved in the disease pathology under the controlled conditions of a scientific laboratory. Thus, induced pluripotent stem cells (iPSC) are already being used to gain insights into the biological mechanisms of several human disorders. Here we review the use of iPSC as a novel tool for disease modeling in the lab. Copyright © 2012 International Society for Advancement of Cytometry. This article was published in Cytometry A and referenced in JBR Journal of Interdisciplinary Medicine and Dental Science

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