alexa Incidence and risk factors for reoperation of surgically treated pelvic organ prolapse.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Tissue Science & Engineering

Author(s): Dllenbach P, Jungo Nancoz C, Eperon I, Dubuisson JB, Boulvain M

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Abstract INTRODUCTION AND HYPOTHESIS: The objective of our study was to estimate the incidence and to identify the risk factors for reoperation of surgically treated pelvic organ prolapse (POP). METHODS: We conducted a nested case-control study among 1,811 women who underwent POP surgery from January 1988 to June 2007. Cases (n = 102) were women who required reoperation for POP following the first intervention through December 2008. Controls (n = 226) were women randomly selected from the same cohort who did not require reoperation. RESULTS: The incidence of POP reoperation was 5.1 per 1,000 women-years. The cumulative incidence was 5.6\%. Risk factors included preoperative prolapse in more than two vaginal compartments (adjusted OR 5.2; 95\% CI 2.8-9.7), history of surgery for POP and/or urinary incontinence (adjusted OR 3.2; 95\% CI 1.5-7.1), and sexual activity (adjusted OR 2.0; 95\% CI 1.0-3.7). CONCLUSIONS: The risk of POP reoperation is relatively low and is associated with preexisting weakness of pelvic tissues. This article was published in Int Urogynecol J and referenced in Journal of Tissue Science & Engineering

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