Author(s): Safavi KH, Muller SA, Suman VJ, Moshell AN, Melton LJ, Safavi KH, Muller SA, Suman VJ, Moshell AN, Melton LJ rd
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Abstract OBJECTIVE: To assess the incidence and natural history of alopecia areata (AA) among unselected patients from a community. DESIGN: We conducted a retrospective population-based descriptive study of AA among residents of Olmsted County, Minnesota, for the period from 1975 through 1989. MATERIAL AND METHODS: After identifying 292 Olmsted County residents first diagnosed with AA during the 15-year study period, we reviewed their complete (inpatient and outpatient) medical records in the community and statistically analyzed the effects of gender and age-group. RESULTS: The overall incidence of AA was 20.2 per 100,000 person-years and did not change with time. Rates were similar in the two genders and over all ages, and lifetime risk was estimated at 1.7\%. Eighty-seven percent of patients were examined by a dermatologist who diagnosed AA, and 29\% of cases were confirmed by biopsy. Most patients had mild or moderate disease, but alopecia totalis or universalis developed at some point during the clinical course in 21 patients. CONCLUSION: This study of the incidence and natural history of AA in a community shows that this disorder is fairly common and can be seen at all ages. Although spontaneous resolution is expected in most patients, a small but significant proportion of cases (probably approximately 7\%) may evolve into severe and chronic hair loss, which may be psychosocially devastating for affected persons.
This article was published in Mayo Clin Proc
and referenced in Journal of Clinical & Experimental Dermatology Research