alexa Incidence of cancer in nodular goitres.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Thyroid Disorders & Therapy

Author(s): Pang HN, Chen CM

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INTRODUCTION: Nodular goitres occur commonly in the population and this paper aims to determine the incidence of thyroid cancer found in these goitres. MATERIALS AND METHODS: This is a retrospective, consecutive analysis of the histology of 268 nodular goitres that had been operated on, from 2002 to 2004, in a single tertiary hospital in Singapore. RESULTS: Fifty-seven goitres (21.2%) with multiple nodules were found to contain a malignancy. Forty-four thyroid cancers (77%) were of the papillary type. The mean age of presentation for benign nodular goitres was 47.9 years. The mean age of presentation for malignant thyroid tumours was 49.25 years. CONCLUSION: The incidence of cancer is significant in nodular goitres and these malignant tumours are usually of the papillary type.

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This article was published in Ann Acad Med Singapore and referenced in Journal of Thyroid Disorders & Therapy

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