alexa Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Siberry GK, Leister E, Jacobson DL, Foster SB, Seage GR rd, , Siberry GK, Leister E, Jacobson DL, Foster SB, Seage GR rd,

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Abstract The incidence of asthma and atopic dermatitis (AD) was evaluated in HIV-infected (n = 451) compared to HIV-exposed (n = 227) but uninfected (HEU) children and adolescents by abstraction from clinical charts. Asthma was more common in HIV-infected compared to HEU children by clinical diagnosis (25\% vs. 20\%, p = 0.101), by asthma medication use, (31\% vs. 22\%, p = 0.012), and by clinical diagnosis and/or medication use, (34\% vs. 25\%, p = 0.012). HIV-infected children had a greater risk of asthma compared to HEU children (HR = 1.37, 95\% CI: 1.01 to 1.86). AD was more common in HIV-infected than HEU children (20\% vs. 12\%, p = 0.009)) and children with AD were more likely to have asthma in both cohorts (41\% vs. 29\%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide. Copyright © 2011 Elsevier Inc. All rights reserved.
This article was published in Clin Immunol and referenced in Journal of AIDS & Clinical Research

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